Subtropical coral reefs such as the lagoonal reefs of Norfolk Island in the MOISTURIZING CONDITIONER remote South Pacific are vastly understudied, with many benthic species unrecorded in the scientific literature.Here we report on ascidian populations from 2021 to 2023 at Norfolk Islands inshore reefs.Quantitative assessments spanning that period w
Zika virus (ZIKV) is a flavivirus that has emerged as a global health threat after the 2015 outbreak in the Americas, where devastating congenital defects were documented.There are currently no vaccines to prevent ZIKV infections nor commercially available clinical diagnostic tests demonstrated to identify ZIKV without cross-reactive interference o
Considering that the precise delivery of Celastrol (Cst) into mitochondria to induce mitochondrial dysfunction may be a potential approach to improve the therapeutic outcomes of Cst on TNBC, a novel tumor mitochondria dual-targeted mixed-micelle nano-system was fabricated via self-synthesized triphenylphosphonium-modified cholesterol (TPP-Chol) and
microRNAs represent promising Sweatpants drugs to treat and prevent several diseases, such as diabetes mellitus.microRNA delivery brings many obstacles to overcome, and one strategy to bypass them is the manufacturing of self-assembled microRNA protein nanoparticles.In this work, a microRNA was combined with the cell-penetrating peptide protamine,